Hmg Treatment For Ovulation Induction
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Hmg treatment for ovulation induction. Fertility medications help cause regular ovulation by stimulating the ovaries to produce mature and release one or more eggs per cycle. If ovulation does not occur after any cycle of therapy the therapeutic regimen employed should be re evaluated 03 38 41. Hmg human menopausal gonadotropin contains both fsh and lh hormones e g. Women who could benefit from treatment cycles with ovulation induction oi medications may have.
It improves the recruitment of follicles by preventing the recruitment of a dominant follicle for the next menstrual cycle. Ovulation induction should be initiated only after a complete and thorough evaluation for infertility. Hmg is typically given to females undergoing fertility treatments like ifv and iui to induce ovulation. Ovulation induction by hmg human menopausal gonadotropin this is a powerful and effective drug.
Commonly prescribed drugs include. Hmg contains the luteinizing hormone lh and follicle stimulating hormone. Gonadotropin ovulation induction treatment cycle also known as controlled ovarian hyperstimulation coh requires careful monitoring of the ovaries with ultrasounds and blood hormone levels every other day. Human menopausal gonadotropin hmg.
When used in in vitro fertilization program ivf this protocol gave a clinical pregnancy rate comparable to pure hmg stimulation at lower expense 6 although msp has been reported to be effective for ovulation induction a widespread search of the literature shows only a few studies using it 6 7. It is a purified extract from the urine of postmenopausal women. Most pregnancies occur in three cycles of a particular therapy. It stimulates the ovaries to produce multiple follicles.
Problems with ovulation are common and account for 25 of female infertility cases. Clomiphene citrate human chorionic gonadotropin follicle stimulating hormone and human menopausal gonadotropin. This treatment therefore improves the quality and quantity of the ovulation thus enhancing pregnancy rates. By the early 1960s common techniques for extracting gonadotropins from the urine of menopausal women human menopausal gonadotropins hmg were developed thus providing a plentiful source of this substance.
Ovulation induction in ovulatory women is typically combined with intrauterine insemination to maximize cycle success. 6 the clinical trials by lunenfeld and colleagues 7 in 1962 resulted in the successful induction of ovulation and pregnancy using hmg. Daily injection of gonadotropins for 7 10 days is used to correct ovulation problems and produce more than one egg. Ovulation induction is also performed in patients who are ovulatory to increase the chance of pregnancy.